Company overview Leiden · The Netherlands
About GenLumina

Building the controllable payload layer for precision oncology.

GenLumina is a preclinical oncology platform company developing a light-activated intracellular payload designed for targeted therapies. We build the core payload technology, activation know-how and IP so that multiple therapeutic programmes can be developed around different targeting biology.

GenLumina team and company culture
A multidisciplinary team combining DNA nanotechnology, physics, oncology drug development, entrepreneurship and business development.
Purpose

Patient impact

Develop a more controllable treatment approach intended to reduce unnecessary exposure of healthy tissue.

Platform

Independent activation control

Molecular targeting determines which cells the construct reaches; light provides a separate spatial activation switch.

Company model

Built for multiple partners

Develop and retain the core platform while building separately agreed programmes around partner-owned antibodies, peptides or ligands.

01 · What brings us together

Different disciplines. One shared platform mission.

GenLumina combines fundamental science, translational oncology, product development and partnering expertise to turn a controllable payload concept into a repeatable platform that can support multiple therapeutic programmes.

Scientific foundation

DNA nanotechnology

The platform builds on research in nanoscale positioning, drug delivery and silver-cluster DNA technology.

Translational focus

From concept to evidence

GenLumina connects laboratory development with preclinical oncology, safety, efficacy, manufacturing and regulatory preparation.

Platform development

Build the reusable core

Internal programmes generate evidence around the payload, conjugation and controlled activation rather than locking the company into one target or indication.

Collaboration

Expand through partners

Pharma and biotech partners can contribute targeting biology, development capabilities and indication expertise for separately defined programmes.

02 · How GenLumina creates value

Build the platform. Validate with partners. License programmes.

GenLumina does not need to independently develop every oncology product to market. The company builds and protects the underlying payload platform, generates transferable evidence through internal programmes and works with pharmaceutical partners to create separately defined therapeutic programmes.

01 · Internal R&D

Build platform evidence

Internal programmes test conjugation, targeting, intracellular delivery, light activation, safety and tumor-cell killing.

Reusable platform knowledge
02 · Partner entry

Bring targeting biology

A pharma or biotech partner can bring an antibody, peptide or ligand relevant to its own pipeline and indication priorities.

Partner-specific PoC
03 · Validation

Decide on evidence

GenLumina and the partner evaluate the combination against predefined technical and biological criteria.

Advance or stop
04 · Commercialization

License successful programmes

A successful PoC can progress through an agreed option toward separately negotiated rights for a defined indication and geographic territory.

Programme-specific licence
GenLumina retains the underlying platform while individual partner programmes can follow their own development, financing and licensing routes.

This allows the same controllable payload technology to support multiple partners, targeting molecules and tumor indications without transferring the entire platform to a single programme.

Explore the partnering model →
03 · Founding team

Science, technology and translation.

The founders combine scientific expertise with the entrepreneurial capability required to develop, protect and partner an emerging oncology platform.

Donny de Bruin

Donny de Bruin, PhD

Founding Partner & Chief Scientific Officer

Donny de Bruin is a biophysicist specializing in DNA nanotechnology, with a focus on theragnostic applications. He has over a decade of experience in DNA for biosensing, nanoscale positioning and drug delivery. His research at Leiden University laid the foundation for GenLumina’s technology.

Prof. Dr. D. Bouwmeester

Prof. Dr. D. Bouwmeester

Founding Partner & Patent Officer

Prof. Dr. Bouwmeester, affiliated with Leiden University and UCSB, is a physicist and recipient of the Spinoza Award. With around 200 publications, his work spans quantum optics and biophysics. He has more than 15 years of experience in silver-cluster DNA technology and its potential therapeutic applications.

Gerco Kanbier

Gerco Kanbier

Founding Partner & Managing Director

Gerco Kanbier has two decades of entrepreneurial experience in technology, cybersecurity and product development. His focus at GenLumina is company development, financing, strategic partnering and translating an emerging scientific platform into a scalable business.

04 · Advisory Board

Experience for the next stage.

Independent expertise in preclinical oncology development and biotech transactions supports GenLumina as the platform moves toward broader validation, partnering and licensing.

Anja Slikkerveer

Anja Slikkerveer

Pre-Clinical Drug Developer Oncology · Advisory Board

Senior preclinical oncology drug developer with expertise in toxicology and metal-based therapies.

Anton Mat

Anton Mat

Business Development · Advisory Board

Senior business developer and dealmaker in the biotech industry with more than 25 years of experience.

05 · Work with GenLumina

Bring your targeting biology.

Pharma and biotech partners can start with a focused partner-specific proof-of-concept. GenLumina provides the controllable payload, enabling know-how and platform IP; a successful programme can create the option to advance through a separately agreed licence.

Explore partnering →